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Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins

Because 2000, Dekker has shifted the most crucial concentrate of his operate to biophysics exactly where he reports the Homes of solitary biomolecules and cells using the tools of nanotechnology. This change of industry was pushed by his fascination for that impressive working of biological molecular buildings, together with because of the prolonged-phrase viewpoint that a lot of interesting discoveries is usually predicted In this particular area.[5] Latest traces of study in his biophysics team are from the regions of:[six]

2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and very first at any time examine of the dynamics DNA supercoils and the invention of supercoil hopping

Immediate immobilization of indigenous yeast iso-1 cytochrome c on bare gold: fast electron relay to redox enzymes and zeptomole protein-movie voltammetry

You are a Christian. If you might make this kind of synthetic cell, would you be just one move closer to God, or would the position of God have diminished to some degree once more?

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‘You shouldn't just give thought to the inquiries of tomorrow, but additionally consider the thoughts with the day after tomorrow’

Dekker started his investigate on single carbon nanotubes in 1993 when he put in place a new line of investigation to check electrical transport by single natural molecules involving nanoelectrodes. In 1996 a breakthrough was realized with carbon nanotubes. This was reached inside of a collaboration With all the team of Nobel laureate Richard Smalley. STM and nanolithography procedures had been accustomed to reveal that these nanotubes are quantum wires at the single-molecule degree, with remarkable Actual physical Qualities.

Considering the fact that 2000 he moved to single-molecule biophysics and nanobiology, with exploration from research of DNA cees dekker loop extrusion and supercoiling to DNA translocation by way of nanopores. More not too long ago his investigate has focused on finding out chromatin structure and mobile division with microorganisms on chip, although he is also aiming to in the end Make synthetic cells from the bottom up.

Nature Physics many thanks the anonymous reviewers for his or her contribution on the peer evaluation of the operate.

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2013, managed shaping of Dwell bacterial cells into arbitrary styles; and discovery of spontaneous fluctuations while in the handedness of histone tetrasomes