A Simple Key For cees dekker Unveiled

Midway by means of his career, Cees Dekker reinvented himself. Soon after years of hardcore physics, he shifted his concentration to ‘nanobiology’ in the convert from the millennium. A expression he coined himself, as a issue of point.

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Multicolor imaging with the bacterial nucleoid and cell division proteins with blue, orange, and close to-infrared fluorescent proteins

Non-equilibrium folding of unique DNA molecules recaptured nearly a thousand situations in a very stable condition nanopore

2010, developed a new way (‘wedging transfer’) to govern nanostructures; initially report of DNA translocation by way of graphene nanopores; and recognized hybrid nanopores by directed insertion of α-hemolysin into strong-state nanopores

Our study ranges from the biophysics of DNA to artificial cells and past. Please take a look beneath within the spectrum of our recent assignments.

All parameters ended up the exact same for every panel On this video clip, except for the Original placement with the 6hb rod (demonstrated in blue) within the ceesdekker.net nanopore. Simulations that terminated early on account of translocation of the rod in the pore are marked by a gray track record.

2011, very first in vitro measurements of transport across a single biomimetic nuclear pore complex; development of multiplexed magnetic tweezers for kilo-molecule experiments; and resolved the system of homology recognition in DNA homologous recombination

The rotors harness energy from the nanoscale drinking water and ion flow that is created by a static chemical or electrochemical prospective gradient within the nanopore, which are recognized through a salt gradient or used voltage, respectively. These artificial nanoengines self-organize and run autonomously in physiological circumstances, suggesting ways to setting up Power-transducing motors at nanoscale interfaces.

It was throughout this period that Dekker performed investigate on magnetic spin units and on sounds in superconductors and semiconductors.

Testing pseudotopological and nontopological designs for SMC-pushed DNA loop extrusion towards roadblock-traversal experiments

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2013, controlled shaping of Stay bacterial cells into arbitrary shapes; and discovery of spontaneous fluctuations from the handedness of histone tetrasomes